Resource StructureDefinition/FHIR Server from package hl7.eu.fhir.idea4rc#current (469 ms)

Resources that use this resource

ConceptMap
subject2FHIR	Subject Model to this guide Map
http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/CancerEpisode	Cancer Episode
http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/HospitalPatientRecords	Hospital Patient Records and Hospital Data
http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/PatientFollowUp	Patient Follow Up

Resources that this resource uses

No resources found

Narrative

Note: links and images are rebased to the (stated) source

Generated Narrative: StructureDefinition Subject

Name	Flags	Card.	Type	Description & Constraints
Subject		0..*	Base	Patient
sex	O	1..*	CodeableConcept	Sex (M) Obligations Actor SHALL:handle Head and Neck SHALL:handle Sarcoma
race	O	1..*	CodeableConcept	Race (M) Obligations Actor SHALL:handle Head and Neck SHALL:handle Sarcoma
birthYear	O	1..*	integer	Birth year (M) Obligations Actor SHALL:handle Head and Neck SHALL:handle Sarcoma
countryOfResidence	O	1..*	CodeableConcept	Country of Residence (M) Obligations Actor SHALL:handle Head and Neck SHALL:handle Sarcoma
smoking	O	1..*	CodeableConcept	Smoking (M) Obligations Actor SHALL:handle Head and Neck SHALL:handle Sarcoma
cigarettesPackYearsSmokedDuringLife	O	0..*	integer	Cigarettes pack years smoked during life (R) Obligations Actor SHALL:handle Head and Neck SHALL:handle Sarcoma
alcohol	O	1..*	CodeableConcept	Alcohol (M) Obligations Actor SHALL:handle Head and Neck SHALL:handle Sarcoma
bmi	O	0..*	Quantity	Height/weight (BMI) (R) Obligations Actor SHALL:handle Head and Neck
charlsonComorbidityIndex	O	0..*	integer	Charlson Comorbidity index (R) Obligations Actor SHALL:handle Head and Neck SHALL:handle Sarcoma
comorbidity	O	1..*	BackboneElement	Comorbidity (M) Obligations Actor SHALL:handle Head and Neck
myocardialInfarction	O	0..*	boolean	Myocardial infarction (O) Obligations Actor SHALL:handle Head and Neck
congestiveHeartFailure	O	0..*	boolean	Congestive heart failure (O) Obligations Actor SHALL:handle Head and Neck
peripheralVascularDisease	O	0..*	boolean	Peripheral vascular disease (O) Obligations Actor SHALL:handle Head and Neck
cerebrovascularAccidentExceptHemiplegia	O	0..*	boolean	Cerebrovascular accident (except hemiplegia) (O) Obligations Actor SHALL:handle Head and Neck
dementia	O	0..*	boolean	Dementia (O) Obligations Actor SHALL:handle Head and Neck
chronicPulmonaryDisease	O	0..*	boolean	Chronic pulmonary disease (O) Obligations Actor SHALL:handle Head and Neck
connectiveTissueDisease	O	0..*	boolean	Connective tissue disease (O) Obligations Actor SHALL:handle Head and Neck
ulcer	O	0..*	boolean	Ulcer (O) Obligations Actor SHALL:handle Head and Neck
mildLiverDisease	O	0..*	boolean	Mild liver disease (O) Obligations Actor SHALL:handle Head and Neck
moderateToSevereLiverDisease	O	0..*	boolean	Moderate to severe liver disease (O) Obligations Actor SHALL:handle Head and Neck
diabetes	O	0..*	boolean	Diabetes (without complications) (O) Obligations Actor SHALL:handle Head and Neck
diabetesWithEndOrganDamage	O	0..*	boolean	Diabetes with end organ damage (O) Obligations Actor SHALL:handle Head and Neck
hemiplegia	O	0..*	boolean	Hemiplegia (O) Obligations Actor SHALL:handle Head and Neck
moderateToSevereRenalDisease	O	0..*	boolean	Moderate to severe renal disease (O) Obligations Actor SHALL:handle Head and Neck
solidTumor	O	0..*	boolean	Solid tumor (non metastatic) (O) Obligations Actor SHALL:handle Head and Neck
metastaticSolidTumor	O	0..*	boolean	Metastatic solid tumor (O) Obligations Actor SHALL:handle Head and Neck
leukemia	O	0..*	boolean	Leukemia (O) Obligations Actor SHALL:handle Head and Neck
lymphoma	O	0..*	boolean	Lymphoma (O) Obligations Actor SHALL:handle Head and Neck
multipleMyeloma	O	0..*	boolean	Multiple myeloma (O) Obligations Actor SHALL:handle Head and Neck
aids	O	0..*	boolean	AIDS (O) Obligations Actor SHALL:handle Head and Neck
ecogPsAtDiagnosis	O	0..*	integer	Eastern Cooperative Oncology Group performance status (ECOG PS) at diagnosis (R) Obligations Actor SHALL:handle Head and Neck
ecogPsLabel	O	0..*	CodeableConcept	ECOG PS label (R) Obligations Actor SHALL:handle Head and Neck
karnofsyIndexAtDiagnosis	O	0..*	integer	Karnofsy index at diagnosis (R) Obligations Actor SHALL:handle Head and Neck
karnofsyIndexLabel	O	0..*	CodeableConcept	Karnofsy index label (R) Obligations Actor SHALL:handle Head and Neck
noGeneticSyndromeWho2020	O	1..*	boolean	No Genetic syndrome (M) Obligations Actor SHALL:handle Sarcoma
olliersDisease	O	1..*	boolean	Olliers disease (M) Obligations Actor SHALL:handle Sarcoma
maffuciSyndrome	O	1..*	boolean	Maffuci syndrome (M) Obligations Actor SHALL:handle Sarcoma
liFraumeniSyndrome	O	1..*	boolean	Li-Fraumeni syndrome (M) Obligations Actor SHALL:handle Sarcoma
mcCuneAlbrightSyndrome	O	1..*	boolean	McCune-Albright syndrome (M) Obligations Actor SHALL:handle Sarcoma
multipleOsteochondromas	O	1..*	boolean	Multiple osteochondromas (M) Obligations Actor SHALL:handle Sarcoma
neurofibromatosisType1	O	1..*	boolean	Neurofibromatosis type 1 (M) Obligations Actor SHALL:handle Sarcoma
rothmundThomsonSyndrome	O	1..*	boolean	Rothmund-Thomson syndrome (M) Obligations Actor SHALL:handle Sarcoma
wernerSyndrome	O	1..*	boolean	Werner syndrome (M) Obligations Actor SHALL:handle Sarcoma
retinoblastoma	O	1..*	boolean	Retinoblastoma (M) Obligations Actor SHALL:handle Sarcoma
pagetDisease	O	1..*	boolean	Paget disease (M) Obligations Actor SHALL:handle Sarcoma
otherSyndromes	O	1..*	CodeableConcept	Other Genetic syndrome (M) Obligations Actor SHALL:handle Sarcoma
previousMalignantCancerSite	O	0..*	CodeableConcept	Previous malignant cancer site (R) Obligations Actor SHALL:handle Head and Neck
previousCancerTreatment	O	1..*	CodeableConcept	Previous cancer treatment (M) Obligations Actor SHALL:handle Sarcoma
Documentation for this format

Source

{
  "resourceType" : "StructureDefinition",
  "id" : "Subject",
  "text" : {
    "status" : "extensions",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: StructureDefinition Subject</b></p><a name=\"Subject\"> </a><a name=\"hcSubject\"> </a><a name=\"Subject-en-US\"> </a><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><tr style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top\"><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"The logical name of the element\">Name</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Information about the use of the element\">Flags</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Minimum and Maximum # of times the element can appear in the instance\">Card.</a></th><th style=\"width: 100px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Reference to the type of the element\">Type</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Additional information about the element\">Description &amp; Constraints</a><span style=\"float: right\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64,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\" alt=\"doco\" style=\"background-color: inherit\"/></a></span></th></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject\" title=\"Subject of care.\nMaturity Level: 0 Draft\">Subject</a><a name=\"Subject\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">*</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://build.fhir.org/types.html#Base\">Base</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Patient</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.sex\" title=\"Describes biological sex as recorded in the patient's identity document or in the hospital record. In the absence of documentation, the one declared by the patient will be recorded \">sex</a><a name=\"Subject.sex\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Sex (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.race\" title=\"Describes race as recorded in  the hospital record, the one declared by the patient,, otherwise, the onerecognized by the observer \nprivacy issues for registering race in France.\n\nHispanic is present only in BB. Hispanic is not mapped as race.\n\nIf Hispanic, OMOP race=0, if not, OMOP ethnicity=\n38003564\n\nIf &quot;hispanic&quot; register ethnicity, otherwise register race\">race</a><a name=\"Subject.race\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Race (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.birthYear\" title=\"Year of birth of the patient. \nPERSON.year_of_birth\">birthYear</a><a name=\"Subject.birthYear\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Birth year (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.countryOfResidence\" title=\"Country of residence at the time of diagnosis \">countryOfResidence</a><a name=\"Subject.countryOfResidence\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Country of Residence (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.smoking\" title=\"Describes tobacco smoker habits within the options proposed \nChanged vocabulary codes to be standard (BLUEBERRY was not)\">smoking</a><a name=\"Subject.smoking\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Smoking (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.cigarettesPackYearsSmokedDuringLife\" title=\"Calculates pack/ year by multiplying the number of packs of cigarettes smoked per day by the number of years the person has been smoking.\n\nRegister the actual value of pack/years in the value_as_number field\">cigarettesPackYearsSmokedDuringLife</a><a name=\"Subject.cigarettesPackYearsSmokedDuringLife\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Cigarettes pack years smoked during life (R)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.alcohol\" title=\"Describes alcohol habits within the options proposed \">alcohol</a><a name=\"Subject.alcohol\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Alcohol (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.bmi\" title=\"Body Mass Index information if weight and height are included. it is calculated as BMI = kg/m2 where kg is a person's weight in kilograms and m2 is their height in metres squared. \nRegister the actual value of BMI centile in the value_as_number field\">bmi</a><a name=\"Subject.bmi\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Quantity\">Quantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Height/weight (BMI)\n (R)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.charlsonComorbidityIndex\" title=\"Provides the Charlson Comorbidity index for the patient \">charlsonComorbidityIndex</a><a name=\"Subject.charlsonComorbidityIndex\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Charlson Comorbidity index (R)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity\" title=\"Describes wherther the patient was diagnosed before treatment of at least one of the comorbidities listed or not. \nIt refers to any disease or medical condition that is simultaneously present with the cancer under study. \">comorbidity</a><a name=\"Subject.comorbidity\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Comorbidity (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.myocardialInfarction\" title=\"Describes comorbidities reported or assesed before treatment. More than one choice is allowed. Please do not include the current cancer in this calculation, only the previous cancer. \">myocardialInfarction</a><a name=\"Subject.comorbidity.myocardialInfarction\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Myocardial infarction (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.congestiveHeartFailure\" title=\"Previous cancer comorbidity related to Congestive heart failure \">congestiveHeartFailure</a><a name=\"Subject.comorbidity.congestiveHeartFailure\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Congestive heart failure (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.peripheralVascularDisease\" title=\"Previous cancer comorbidity related to Peripheral vascular disease \">peripheralVascularDisease</a><a name=\"Subject.comorbidity.peripheralVascularDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Peripheral vascular disease (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia\" title=\"Previous cancer comorbidity related to Cerebrovascular accident  (except hemiplegia) \">cerebrovascularAccidentExceptHemiplegia</a><a name=\"Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Cerebrovascular accident  (except hemiplegia) (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.dementia\" title=\"Previous cancer comorbidity related to Dementia \">dementia</a><a name=\"Subject.comorbidity.dementia\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Dementia (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.chronicPulmonaryDisease\" title=\"Previous cancer comorbidity related to Chronic pulmonary disease \">chronicPulmonaryDisease</a><a name=\"Subject.comorbidity.chronicPulmonaryDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Chronic pulmonary disease (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.connectiveTissueDisease\" title=\"Previous cancer comorbidity related to Connective tissue disease \">connectiveTissueDisease</a><a name=\"Subject.comorbidity.connectiveTissueDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Connective tissue disease (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.ulcer\" title=\"Previous cancer comorbidity related to Ulcer \nCouldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351\">ulcer</a><a name=\"Subject.comorbidity.ulcer\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Ulcer (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.mildLiverDisease\" title=\"Previous cancer comorbidity related to Mild liver disease \">mildLiverDisease</a><a name=\"Subject.comorbidity.mildLiverDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Mild liver disease (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.moderateToSevereLiverDisease\" title=\"Previous cancer comorbidity related to Moderate to severe liver disease \nSame as Moderate to severe renal disease\">moderateToSevereLiverDisease</a><a name=\"Subject.comorbidity.moderateToSevereLiverDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Moderate to severe liver disease (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.diabetes\" title=\"Previous cancer comorbidity related to Diabetes (without complications) \">diabetes</a><a name=\"Subject.comorbidity.diabetes\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Diabetes (without complications) (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.diabetesWithEndOrganDamage\" title=\"Previous cancer comorbidity related to Diabetes with end organ damage \">diabetesWithEndOrganDamage</a><a name=\"Subject.comorbidity.diabetesWithEndOrganDamage\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Diabetes with end organ damage (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.hemiplegia\" title=\"Previous cancer comorbidity related to Hemiplegia \nCouldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351\">hemiplegia</a><a name=\"Subject.comorbidity.hemiplegia\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Hemiplegia (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.moderateToSevereRenalDisease\" title=\"Previous cancer comorbidity related to Moderate to severe renal disease \nSame as Moderate to severe liver disease\">moderateToSevereRenalDisease</a><a name=\"Subject.comorbidity.moderateToSevereRenalDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Moderate to severe renal disease (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.solidTumor\" title=\"Previous cancer comorbidity related to Solid tumor (non metastatic) \nHistory of event + Other cancer (find the corresponding standard concept)\n\nCouldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351\n\nIT NEEDS TO BE PRESENTED\">solidTumor</a><a name=\"Subject.comorbidity.solidTumor\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Solid tumor (non metastatic) (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.metastaticSolidTumor\" title=\"Previous cancer comorbidity related to Metastatic solid tumor \nHistory of event + Other cancer (find the corresponding standard concept)\">metastaticSolidTumor</a><a name=\"Subject.comorbidity.metastaticSolidTumor\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Metastatic solid tumor (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.leukemia\" title=\"Previous cancer comorbidity related to Leukemia \nHistory of event + Leukemia\n\nCouldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351\">leukemia</a><a name=\"Subject.comorbidity.leukemia\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Leukemia (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.lymphoma\" title=\"Previous cancer comorbidity related to Lymphoma \nHistory of event + Malignant Lymphoma NOS\n\nCouldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351\">lymphoma</a><a name=\"Subject.comorbidity.lymphoma\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Lymphoma (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.multipleMyeloma\" title=\"Previous cancer comorbidity related to Multiple myeloma \nHistory of event + Multiple myeloma \n\nCouldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351\">multipleMyeloma</a><a name=\"Subject.comorbidity.multipleMyeloma\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Multiple myeloma (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.aids\" title=\"Previous cancer comorbidity related to AIDS \nHistory of event + AIDS \">aids</a><a name=\"Subject.comorbidity.aids\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">AIDS (O)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.ecogPsAtDiagnosis\" title=\"Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis \">ecogPsAtDiagnosis</a><a name=\"Subject.ecogPsAtDiagnosis\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis (R)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.ecogPsLabel\" title=\"Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis \">ecogPsLabel</a><a name=\"Subject.ecogPsLabel\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">ECOG PS label (R)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.karnofsyIndexAtDiagnosis\" title=\"Karnofsy index at diagnosis. Consider only the first KI before any treatment available in the clinical record. \">karnofsyIndexAtDiagnosis</a><a name=\"Subject.karnofsyIndexAtDiagnosis\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Karnofsy index at diagnosis (R)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.karnofsyIndexLabel\" title=\"Karnofsy index at diagnosis. Consider only the first KI before any treatment available in the clinical record. \">karnofsyIndexLabel</a><a name=\"Subject.karnofsyIndexLabel\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Karnofsy index label (R)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020\" title=\"If no genetic syndrome was identified for the patient. based on WHO 2020. \nuse 37204336 [Genetic disease] as value_as_concept_id\">noGeneticSyndromeWho2020</a><a name=\"Subject.noGeneticSyndromeWho2020\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">No Genetic syndrome (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.olliersDisease\" title=\"If patient presents Olliers disease \">olliersDisease</a><a name=\"Subject.noGeneticSyndromeWho2020.olliersDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Olliers disease (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.maffuciSyndrome\" title=\"If patient presents Maffuci syndrome \">maffuciSyndrome</a><a name=\"Subject.noGeneticSyndromeWho2020.maffuciSyndrome\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Maffuci syndrome (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome\" title=\"If patient presents Li-Fraumeni syndrome \">liFraumeniSyndrome</a><a name=\"Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Li-Fraumeni syndrome (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome\" title=\"If patient presents McCune-Albright syndrome \">mcCuneAlbrightSyndrome</a><a name=\"Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">McCune-Albright syndrome (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.multipleOsteochondromas\" title=\"If patient presents Multiple osteochondromas \">multipleOsteochondromas</a><a name=\"Subject.noGeneticSyndromeWho2020.multipleOsteochondromas\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Multiple osteochondromas (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.neurofibromatosisType1\" title=\"If patient presents Neurofibromatosis type 1 \">neurofibromatosisType1</a><a name=\"Subject.noGeneticSyndromeWho2020.neurofibromatosisType1\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Neurofibromatosis type 1 (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome\" title=\"If patient presents Rothmund-Thomson syndrome \">rothmundThomsonSyndrome</a><a name=\"Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Rothmund-Thomson syndrome (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.wernerSyndrome\" title=\"If patient presents Werner syndrome \">wernerSyndrome</a><a name=\"Subject.noGeneticSyndromeWho2020.wernerSyndrome\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Werner syndrome (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.retinoblastoma\" title=\"If patient presents Retinoblastoma \">retinoblastoma</a><a name=\"Subject.noGeneticSyndromeWho2020.retinoblastoma\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Retinoblastoma (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.pagetDisease\" title=\"If patient presents Paget disease \">pagetDisease</a><a name=\"Subject.noGeneticSyndromeWho2020.pagetDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Paget disease (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.otherSyndromes\" title=\"If patient presents Other Genetic syndrome. According to WHO 2020 \nHistory of event + \nOther genetic syndrome (find the corresponding standard concept)\nIf not specified, use 37204336 [Genetic disease]\">otherSyndromes</a><a name=\"Subject.noGeneticSyndromeWho2020.otherSyndromes\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Other Genetic syndrome (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.previousMalignantCancerSite\" title=\"Describes the site of the malignant tumour reported or assesed before the cancer under study. Any type of of solid and haematological cancer is listed. To obtain the previous malignant cancer refer to the solid tumor (metastatic and non-metastatic)  comorbidity \nHistory of event + \nCancer modifier for site\">previousMalignantCancerSite</a><a name=\"Subject.previousMalignantCancerSite\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Previous malignant cancer site (R)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\">Head and Neck</a></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck00.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.previousCancerTreatment\" title=\"Describes the type of treatment performed for the previous cancer \nHistory of event + \nOther treatment (find the corresponding standard concept)\nIf not specified,\">previousCancerTreatment</a><a name=\"Subject.previousCancerTreatment\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Previous cancer treatment (M)<br/><table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\">Sarcoma</a></td></tr></table></td></tr>\r\n<tr><td colspan=\"5\" class=\"hierarchy\"><br/><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64,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\" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table></div>"
  },
  "url" : "http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject",
  "version" : "0.1.0",
  "name" : "SubjectI4rc",
  "title" : "Patient",
  "status" : "draft",
  "date" : "2025-01-13T10:15:12+00:00",
  "publisher" : "IDEA4RC Project",
  "contact" : [
    {
      "name" : "IDEA4RC Project",
      "telecom" : [
        {
          "system" : "url",
          "value" : "https://www.idea4rc.eu/"
        }
      ]
    },
    {
      "name" : "IDEA4RC Project",
      "telecom" : [
        {
          "system" : "url",
          "value" : "https://www.idea4rc.eu/"
        }
      ]
    }
  ],
  "description" : "Subject of care.\nMaturity Level: 0 Draft",
  "jurisdiction" : [
    {
      "coding" : [
        {
          "system" : "http://unstats.un.org/unsd/methods/m49/m49.htm",
          "code" : "150",
          "display" : "Europe"
        }
      ]
    }
  ],
  "fhirVersion" : "4.0.1",
  "kind" : "logical",
  "abstract" : false,
  "type" : "http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject",
  "baseDefinition" : "http://hl7.org/fhir/StructureDefinition/Base",
  "derivation" : "specialization",
  "snapshot" : {
    "element" : [
      {
        "id" : "Subject",
        "path" : "Subject",
        "short" : "Patient",
        "definition" : "Subject of care.\nMaturity Level: 0 Draft",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Base",
          "min" : 0,
          "max" : "*"
        },
        "isModifier" : false
      },
      {
        "id" : "Subject.sex",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.sex",
        "short" : "Sex (M)",
        "definition" : "Describes biological sex as recorded in the patient's identity document or in the hospital record. In the absence of documentation, the one declared by the patient will be recorded",
        "comment" : "Male - 8507\nFemale - 8532",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.sex",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.race",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.race",
        "short" : "Race (M)",
        "definition" : "Describes race as recorded in  the hospital record, the one declared by the patient,, otherwise, the onerecognized by the observer \nprivacy issues for registering race in France.\n\nHispanic is present only in BB. Hispanic is not mapped as race.\n\nIf Hispanic, OMOP race=0, if not, OMOP ethnicity=\n38003564\n\nIf \"hispanic\" register ethnicity, otherwise register race",
        "comment" : "White - 8527\nBlack - 8516\nAsian/Pacific Islanders - 8515\nAmerican Indian/Alaska Native - 8657\n        Hispanic or Latino - 38003563",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.race",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.birthYear",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.birthYear",
        "short" : "Birth year (M)",
        "definition" : "Year of birth of the patient. \nPERSON.year_of_birth",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.birthYear",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.countryOfResidence",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.countryOfResidence",
        "short" : "Country of Residence (M)",
        "definition" : "Country of residence at the time of diagnosis",
        "comment" : "Son in the hierarchy of countries",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.countryOfResidence",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.smoking",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.smoking",
        "short" : "Smoking (M)",
        "definition" : "Describes tobacco smoker habits within the options proposed \nChanged vocabulary codes to be standard (BLUEBERRY was not)",
        "comment" : "Current smoker - 36309332\nFormer smoker - 45883458\nNever smoker - 45879404",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.smoking",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.cigarettesPackYearsSmokedDuringLife",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.cigarettesPackYearsSmokedDuringLife",
        "short" : "Cigarettes pack years smoked during life (R)",
        "definition" : "Calculates pack/ year by multiplying the number of packs of cigarettes smoked per day by the number of years the person has been smoking.\n\nRegister the actual value of pack/years in the value_as_number field",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Subject.cigarettesPackYearsSmokedDuringLife",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.alcohol",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.alcohol",
        "short" : "Alcohol (M)",
        "definition" : "Describes alcohol habits within the options proposed",
        "comment" : "Current drinker - 4074035\nEx-drinker - 4220362\nLifetime non-drinker of alcohol - 37204556\nEx-problem drinker - 4117706",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.alcohol",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.bmi",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.bmi",
        "short" : "Height/weight (BMI)\n (R)",
        "definition" : "Body Mass Index information if weight and height are included. it is calculated as BMI = kg/m2 where kg is a person's weight in kilograms and m2 is their height in metres squared. \nRegister the actual value of BMI centile in the value_as_number field",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Subject.bmi",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Quantity"
          }
        ]
      },
      {
        "id" : "Subject.charlsonComorbidityIndex",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.charlsonComorbidityIndex",
        "short" : "Charlson Comorbidity index (R)",
        "definition" : "Provides the Charlson Comorbidity index for the patient",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Subject.charlsonComorbidityIndex",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity",
        "short" : "Comorbidity (M)",
        "definition" : "Describes wherther the patient was diagnosed before treatment of at least one of the comorbidities listed or not. \nIt refers to any disease or medical condition that is simultaneously present with the cancer under study.",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.comorbidity",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "BackboneElement"
          }
        ],
        "constraint" : [
          {
            "key" : "ele-1",
            "severity" : "error",
            "human" : "All FHIR elements must have a @value or children",
            "expression" : "hasValue() or (children().count() > id.count())",
            "xpath" : "@value|f:*|h:div",
            "source" : "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.id",
        "path" : "Subject.comorbidity.id",
        "representation" : [
          "xmlAttr"
        ],
        "short" : "Unique id for inter-element referencing",
        "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Element.id",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl" : "string"
              }
            ],
            "code" : "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "n/a"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.extension",
        "path" : "Subject.comorbidity.extension",
        "slicing" : {
          "discriminator" : [
            {
              "type" : "value",
              "path" : "url"
            }
          ],
          "description" : "Extensions are always sliced by (at least) url",
          "rules" : "open"
        },
        "short" : "Additional content defined by implementations",
        "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias" : [
          "extensions",
          "user content"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Element.extension",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Extension"
          }
        ],
        "constraint" : [
          {
            "key" : "ele-1",
            "severity" : "error",
            "human" : "All FHIR elements must have a @value or children",
            "expression" : "hasValue() or (children().count() > id.count())",
            "xpath" : "@value|f:*|h:div",
            "source" : "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key" : "ext-1",
            "severity" : "error",
            "human" : "Must have either extensions or value[x], not both",
            "expression" : "extension.exists() != value.exists()",
            "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "n/a"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.modifierExtension",
        "path" : "Subject.comorbidity.modifierExtension",
        "short" : "Extensions that cannot be ignored even if unrecognized",
        "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
        "alias" : [
          "extensions",
          "user content",
          "modifiers"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "BackboneElement.modifierExtension",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Extension"
          }
        ],
        "constraint" : [
          {
            "key" : "ele-1",
            "severity" : "error",
            "human" : "All FHIR elements must have a @value or children",
            "expression" : "hasValue() or (children().count() > id.count())",
            "xpath" : "@value|f:*|h:div",
            "source" : "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key" : "ext-1",
            "severity" : "error",
            "human" : "Must have either extensions or value[x], not both",
            "expression" : "extension.exists() != value.exists()",
            "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier" : true,
        "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "N/A"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.myocardialInfarction",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.myocardialInfarction",
        "short" : "Myocardial infarction (O)",
        "definition" : "Describes comorbidities reported or assesed before treatment. More than one choice is allowed. Please do not include the current cancer in this calculation, only the previous cancer.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Subject.comorbidity.myocardialInfarction",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.congestiveHeartFailure",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.congestiveHeartFailure",
        "short" : "Congestive heart failure (O)",
        "definition" : "Previous cancer comorbidity related to Congestive heart failure",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Subject.comorbidity.congestiveHeartFailure",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.peripheralVascularDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.peripheralVascularDisease",
        "short" : "Peripheral vascular disease (O)",
        "definition" : "Previous cancer comorbidity related to Peripheral vascular disease",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Subject.comorbidity.peripheralVascularDisease",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia",
        "short" : "Cerebrovascular accident  (except hemiplegia) (O)",
        "definition" : "Previous cancer comorbidity related to Cerebrovascular accident  (except hemiplegia)",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.dementia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.dementia",
        "short" : "Dementia (O)",
        "definition" : "Previous cancer comorbidity related to Dementia",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Subject.comorbidity.dementia",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.chronicPulmonaryDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.chronicPulmonaryDisease",
        "short" : "Chronic pulmonary disease (O)",
        "definition" : "Previous cancer comorbidity related to Chronic pulmonary disease",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Subject.comorbidity.chronicPulmonaryDisease",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.connectiveTissueDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
  &nbomatosisType1",
        "short" : "Neurofibromatosis type 1 (M)",
        "definition" : "If patient presents Neurofibromatosis type 1",
        "comment" : "Neurofibromatosis type 1 - 377252",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.neurofibromatosisType1",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome",
        "short" : "Rothmund-Thomson syndrome (M)",
        "definition" : "If patient presents Rothmund-Thomson syndrome",
        "comment" : "Rothmund-Thomson syndrome - 4286355",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.wernerSyndrome",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.wernerSyndrome",
        "short" : "Werner syndrome (M)",
        "definition" : "If patient presents Werner syndrome",
        "comment" : "Werner syndrome - 4197821",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.wernerSyndrome",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.retinoblastoma",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.retinoblastoma",
        "short" : "Retinoblastoma (M)",
        "definition" : "If patient presents Retinoblastoma",
        "comment" : "Retinoblastoma - 4158977",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.retinoblastoma",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.pagetDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.pagetDisease",
        "short" : "Paget disease (M)",
        "definition" : "If patient presents Paget disease",
        "comment" : "Osteitis deformans - 75910",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.pagetDisease",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.otherSyndromes",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.otherSyndromes",
        "short" : "Other Genetic syndrome (M)",
        "definition" : "If patient presents Other Genetic syndrome. According to WHO 2020 \nHistory of event + \nOther genetic syndrome (find the corresponding standard concept)\nIf not specified, use 37204336 [Genetic disease]",
        "comment" : "History of event - 1340204\n\n+ Any Standard Condition Code\nIf not specified, use 37204336 [Genetic disease]",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.otherSyndromes",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.previousMalignantCancerSite",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.previousMalignantCancerSite",
        "short" : "Previous malignant cancer site (R)",
        "definition" : "Describes the site of the malignant tumour reported or assesed before the cancer under study. Any type of of solid and haematological cancer is listed. To obtain the previous malignant cancer refer to the solid tumor (metastatic and non-metastatic)  comorbidity \nHistory of event + \nCancer modifier for site",
        "comment" : "Values from CancerModifier Topography\n\nUse integer for IDEA4RC if needed",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Subject.previousMalignantCancerSite",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.previousCancerTreatment",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.previousCancerTreatment",
        "short" : "Previous cancer treatment (M)",
        "definition" : "Describes the type of treatment performed for the previous cancer \nHistory of event + \nOther treatment (find the corresponding standard concept)\nIf not specified,",
        "comment" : "Chemotherapy - 4273629\nRadiation oncology- 4170755\nSurgery - 4121697 \nComprehensive medication therapy review - 42535584\nImmunological therapy - 4295112",
        "min" : 1,
        "max" : "*",
        "base" : {
          "path" : "Subject.previousCancerTreatment",
          "min" : 1,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      }
    ]
  },
  "differential" : {
    "element" : [
      {
        "id" : "Subject",
        "path" : "Subject",
        "short" : "Patient",
        "definition" : "Subject of care.\nMaturity Level: 0 Draft"
      },
      {
        "id" : "Subject.sex",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.sex",
        "short" : "Sex (M)",
        "definition" : "Describes biological sex as recorded in the patient's identity document or in the hospital record. In the absence of documentation, the one declared by the patient will be recorded ",
        "comment" : "Male - 8507\nFemale - 8532",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.race",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.race",
        "short" : "Race (M)",
        "definition" : "Describes race as recorded in  the hospital record, the one declared by the patient,, otherwise, the onerecognized by the observer \nprivacy issues for registering race in France.\n\nHispanic is present only in BB. Hispanic is not mapped as race.\n\nIf Hispanic, OMOP race=0, if not, OMOP ethnicity=\n38003564\n\nIf \"hispanic\" register ethnicity, otherwise register race",
        "comment" : "White - 8527\nBlack - 8516\nAsian/Pacific Islanders - 8515\nAmerican Indian/Alaska Native - 8657\n        Hispanic or Latino - 38003563",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.birthYear",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.birthYear",
        "short" : "Birth year (M)",
        "definition" : "Year of birth of the patient. \nPERSON.year_of_birth",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.countryOfResidence",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.countryOfResidence",
        "short" : "Country of Residence (M)",
        "definition" : "Country of residence at the time of diagnosis ",
        "comment" : "Son in the hierarchy of countries",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.smoking",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.smoking",
        "short" : "Smoking (M)",
        "definition" : "Describes tobacco smoker habits within the options proposed \nChanged vocabulary codes to be standard (BLUEBERRY was not)",
        "comment" : "Current smoker - 36309332\nFormer smoker - 45883458\nNever smoker - 45879404",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.cigarettesPackYearsSmokedDuringLife",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.cigarettesPackYearsSmokedDuringLife",
        "short" : "Cigarettes pack years smoked during life (R)",
        "definition" : "Calculates pack/ year by multiplying the number of packs of cigarettes smoked per day by the number of years the person has been smoking.\n\nRegister the actual value of pack/years in the value_as_number field",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.alcohol",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.alcohol",
        "short" : "Alcohol (M)",
        "definition" : "Describes alcohol habits within the options proposed ",
        "comment" : "Current drinker - 4074035\nEx-drinker - 4220362\nLifetime non-drinker of alcohol - 37204556\nEx-problem drinker - 4117706",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.bmi",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.bmi",
        "short" : "Height/weight (BMI)\n (R)",
        "definition" : "Body Mass Index information if weight and height are included. it is calculated as BMI = kg/m2 where kg is a person's weight in kilograms and m2 is their height in metres squared. \nRegister the actual value of BMI centile in the value_as_number field",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "Quantity"
          }
        ]
      },
      {
        "id" : "Subject.charlsonComorbidityIndex",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.charlsonComorbidityIndex",
        "short" : "Charlson Comorbidity index (R)",
        "definition" : "Provides the Charlson Comorbidity index for the patient ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity",
        "short" : "Comorbidity (M)",
        "definition" : "Describes wherther the patient was diagnosed before treatment of at least one of the comorbidities listed or not. \nIt refers to any disease or medical condition that is simultaneously present with the cancer under study. ",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "BackboneElement"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.myocardialInfarction",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.myocardialInfarction",
        "short" : "Myocardial infarction (O)",
        "definition" : "Describes comorbidities reported or assesed before treatment. More than one choice is allowed. Please do not include the current cancer in this calculation, only the previous cancer. ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.congestiveHeartFailure",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.congestiveHeartFailure",
        "short" : "Congestive heart failure (O)",
        "definition" : "Previous cancer comorbidity related to Congestive heart failure ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.peripheralVascularDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.peripheralVascularDisease",
        "short" : "Peripheral vascular disease (O)",
        "definition" : "Previous cancer comorbidity related to Peripheral vascular disease ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia",
        "short" : "Cerebrovascular accident  (except hemiplegia) (O)",
        "definition" : "Previous cancer comorbidity related to Cerebrovascular accident  (except hemiplegia) ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.dementia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.dementia",
        "short" : "Dementia (O)",
        "definition" : "Previous cancer comorbidity related to Dementia ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.chronicPulmonaryDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.chronicPulmonaryDisease",
        "short" : "Chronic pulmonary disease (O)",
        "definition" : "Previous cancer comorbidity related to Chronic pulmonary disease ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.connectiveTissueDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.connectiveTissueDisease",
        "short" : "Connective tissue disease (O)",
        "definition" : "Previous cancer comorbidity related to Connective tissue disease ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.ulcer",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.ulcer",
        "short" : "Ulcer (O)",
        "definition" : "Previous cancer comorbidity related to Ulcer \nCouldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.mildLiverDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.mildLiverDisease",
        "short" : "Mild liver disease (O)",
        "definition" : "Previous cancer comorbidity related to Mild liver disease ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.moderateToSevereLiverDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.moderateToSevereLiverDisease",
        "short" : "Moderate to severe liver disease (O)",
        "definition" : "Previous cancer comorbidity related to Moderate to severe liver disease \nSame as Moderate to severe renal disease",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.diabetes",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.diabetes",
        "short" : "Diabetes (without complications) (O)",
        "definition" : "Previous cancer comorbidity related to Diabetes (without complications) ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.diabetesWithEndOrganDamage",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.diabetesWithEndOrganDamage",
        "short" : "Diabetes with end organ damage (O)",
        "definition" : "Previous cancer comorbidity related to Diabetes with end organ damage ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.hemiplegia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.hemiplegia",
        "short" : "Hemiplegia (O)",
        "definition" : "Previous cancer comorbidity related to Hemiplegia \nCouldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.moderateToSevereRenalDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.moderateToSevereRenalDisease",
        "short" : "Moderate to severe renal disease (O)",
        "definition" : "Previous cancer comorbidity related to Moderate to severe renal disease \nSame as Moderate to severe liver disease",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.solidTumor",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.solidTumor",
        "short" : "Solid tumor (non metastatic) (O)",
        "definition" : "Previous cancer comorbidity related to Solid tumor (non metastatic) \nHistory of event + Other cancer (find the corresponding standard concept)\n\nCouldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351\n\nIT NEEDS TO BE PRESENTED",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.metastaticSolidTumor",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.metastaticSolidTumor",
        "short" : "Metastatic solid tumor (O)",
        "definition" : "Previous cancer comorbidity related to Metastatic solid tumor \nHistory of event + Other cancer (find the corresponding standard concept)",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.leukemia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.leukemia",
        "short" : "Leukemia (O)",
        "definition" : "Previous cancer comorbidity related to Leukemia \nHistory of event + Leukemia\n\nCouldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.lymphoma",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.lymphoma",
        "short" : "Lymphoma (O)",
        "definition" : "Previous cancer comorbidity related to Lymphoma \nHistory of event + Malignant Lymphoma NOS\n\nCouldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.multipleMyeloma",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.multipleMyeloma",
        "short" : "Multiple myeloma (O)",
        "definition" : "Previous cancer comorbidity related to Multiple myeloma \nHistory of event + Multiple myeloma \n\nCouldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.aids",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.aids",
        "short" : "AIDS (O)",
        "definition" : "Previous cancer comorbidity related to AIDS \nHistory of event + AIDS ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.ecogPsAtDiagnosis",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.ecogPsAtDiagnosis",
        "short" : "Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis (R)",
        "definition" : "Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.ecogPsLabel",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.ecogPsLabel",
        "short" : "ECOG PS label (R)",
        "definition" : "Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis ",
        "comment" : "Answers of ECOG Performance Status [Interpretation] - 36303470",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.karnofsyIndexAtDiagnosis",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.karnofsyIndexAtDiagnosis",
        "short" : "Karnofsy index at diagnosis (R)",
        "definition" : "Karnofsy index at diagnosis. Consider only the first KI before any treatment available in the clinical record. ",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.karnofsyIndexLabel",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.karnofsyIndexLabel",
        "short" : "Karnofsy index label (R)",
        "definition" : "Karnofsy index at diagnosis. Consider only the first KI before any treatment available in the clinical record. ",
        "comment" : "Answers of Karnofsky Performance Status [Interpretation] - 36303744",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020",
        "short" : "No Genetic syndrome (M)",
        "definition" : "If no genetic syndrome was identified for the patient. based on WHO 2020. \nuse 37204336 [Genetic disease] as value_as_concept_id",
        "comment" : "No evidence of - 4211787",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.olliersDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.olliersDisease",
        "short" : "Olliers disease (M)",
        "definition" : "If patient presents Olliers disease ",
        "comment" : "Enchondromatosis - 4145177",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.maffuciSyndrome",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.maffuciSyndrome",
        "short" : "Maffuci syndrome (M)",
        "definition" : "If patient presents Maffuci syndrome ",
        "comment" : "Maffucci syndrome - 4187683",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome",
        "short" : "Li-Fraumeni syndrome (M)",
        "definition" : "If patient presents Li-Fraumeni syndrome ",
        "comment" : "Li-Fraumeni syndrome - 4323645",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome",
        "short" : "McCune-Albright syndrome (M)",
        "definition" : "If patient presents McCune-Albright syndrome ",
        "comment" : "McCune Albright syndrome - 37117262",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.multipleOsteochondromas",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.multipleOsteochondromas",
        "short" : "Multiple osteochondromas (M)",
        "definition" : "If patient presents Multiple osteochondromas ",
        "comment" : "Multiple osteochondroma - 37396802",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.neurofibromatosisType1",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.neurofibromatosisType1",
        "short" : "Neurofibromatosis type 1 (M)",
        "definition" : "If patient presents Neurofibromatosis type 1 ",
        "comment" : "Neurofibromatosis type 1 - 377252",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome",
        "short" : "Rothmund-Thomson syndrome (M)",
        "definition" : "If patient presents Rothmund-Thomson syndrome ",
        "comment" : "Rothmund-Thomson syndrome - 4286355",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.wernerSyndrome",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.wernerSyndrome",
        "short" : "Werner syndrome (M)",
        "definition" : "If patient presents Werner syndrome ",
        "comment" : "Werner syndrome - 4197821",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.retinoblastoma",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.retinoblastoma",
        "short" : "Retinoblastoma (M)",
        "definition" : "If patient presents Retinoblastoma ",
        "comment" : "Retinoblastoma - 4158977",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.pagetDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.pagetDisease",
        "short" : "Paget disease (M)",
        "definition" : "If patient presents Paget disease ",
        "comment" : "Osteitis deformans - 75910",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.otherSyndromes",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.otherSyndromes",
        "short" : "Other Genetic syndrome (M)",
        "definition" : "If patient presents Other Genetic syndrome. According to WHO 2020 \nHistory of event + \nOther genetic syndrome (find the corresponding standard concept)\nIf not specified, use 37204336 [Genetic disease]",
        "comment" : "History of event - 1340204\n\n+ Any Standard Condition Code\nIf not specified, use 37204336 [Genetic disease]",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.previousMalignantCancerSite",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.previousMalignantCancerSite",
        "short" : "Previous malignant cancer site (R)",
        "definition" : "Describes the site of the malignant tumour reported or assesed before the cancer under study. Any type of of solid and haematological cancer is listed. To obtain the previous malignant cancer refer to the solid tumor (metastatic and non-metastatic)  comorbidity \nHistory of event + \nCancer modifier for site",
        "comment" : "Values from CancerModifier Topography\n\nUse integer for IDEA4RC if needed",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.previousCancerTreatment",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.previousCancerTreatment",
        "short" : "Previous cancer treatment (M)",
        "definition" : "Describes the type of treatment performed for the previous cancer \nHistory of event + \nOther treatment (find the corresponding standard concept)\nIf not specified,",
        "comment" : "Chemotherapy - 4273629\nRadiation oncology- 4170755\nSurgery - 4121697 \nComprehensive medication therapy review - 42535584\nImmunological therapy - 4295112",
        "min" : 1,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      }
    ]
  }
}

XIG built as of ??metadata-date??. Found ??metadata-resources?? resources in ??metadata-packages?? packages.